On January 20, 2021, Joseph R. Biden became the 46th president of the US. ASCA reviewed the first year of the Biden administration’s health actions in the January 2022 Regulatory Review column. That first year, Biden and his team largely focused on installing political appointees to important executive branch roles such as the secretary of the US Department of Health & Human Services (HHS) and director for the Centers for Disease Control and Prevention (CDC). The primary health policy priority for the administration’s new leaders and their agencies was, at that time, the COVID-19 pandemic. Nevertheless, major health reform considerations, such as new federal prohibitions against surprise medical billing scheduled to take effect in 2022, were already on the horizon. Now, three years into Biden’s presidency, ASCA takes stock of the administration’s health-related actions and other current issues that will shape health policy conversations in future years.